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Friday, March 22, 2019

Review of Research Paper on Creating Home-Made Stem Cells

Our paper discusses an important step in the enquiry surrounding foot carrells. Pluripotent paper booths are found in the early blastocyst, and can differentiate into different cell types such as neurons, cardiac muscle, or blood cells.As is explained elsewhere on this paper, stem cells are extremely useful and hold amazing medical potential, in particular to grow specific cells, tissues, and even organs for patients. Controversy mires the progress of stem cell research from embryos, however, and technical problems exist along with the ethical ones. Marius Wernig and his team up of scientists have had success studying a way to get about this, however. What if, instead of taking stem cells from newly created embryos, an individuals witness cells could be used? The cells in the adult body are no longer stem cells they arent pluripotent, and can only be a certain type. But with special techniques, its actually possible to wee these adult cells to become stem ce lls, with a pluripotency that allows them to develop into whatever cell type is needed In this experiment, induced pluripotent stem cells were created using the fibroblast cells from mice. Fibroblasts were upstage from underneath the skin of the subject mice. In order to revert the cell back to a induced pluripotent state, quaternity specially selected transcription factors (Oct 4, Sox 2, c-Myc and Klf4) were used. These four transcription factors were each merged into the DNA of a virus that lacked the capability to infect, and the fibroblasts were exposed to these viruses. Just like normal viruses, these injected their DNA into the fibroblast cells, and the DNA was incorporated into the cell. Now the fibroblasts contained the new transcription ... ... become a breeding state for debate as well as a popular political platform for presidential candidates. These topics have also become very partisan issues, Democrats cosmos known to fully support stem cell research and R epublicans creation known to disagree with the practices involved with it. In 2004, stem cell research was a particularly hot topic, and it is commonly thought that President scrubs second term was won that year due to his strength on embryonic stem cell research. He thought is was wrong to create any more embryonic stem cell lines, that that the use of the existing ones for research was acceptable.Works Cited Wernig, Marius, Alexander Meissner, Ruth Foreman, Tobias Brambrink, Manching Ku, Konrad Hochedlinger, Bradley E. Bernstein & Rudolf Jaenisch. In vitro reprogramming of fibroblasts into pluripotent ES-cell-like state. Nature 448(2007) 318-325.

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